Predicting Pathologic Stage

Partin Coefficient Table II: PSA = 4.1 – 10.0 ng/ml

This table shows the probability of having each of the four pathologic stages of prostate cancer based on Gleason score, clinical stage and a PSA level between 4.1 and 10.0 ng/ml.

Examples

• A man with a PSA level of 5.3 ng/ml, a Gleason score of 3 and a clinical stage of T1c has an 83% chance of having organ-confined disease.
  
  
• A man with a PSA level of 7.7 ng/ml, a Gleason score of 7 and a clinical stage of T2c has an 18% chance of seminal vesicle involvement.

PSA = 4.1 – 10.0 ng/ml

Probability of Pathologic Stage (%)

		Clinical Stage
Gleason score	Pathologic stage	T1a	T1b	T1c	T2a	T2b	T2c	T3a
2-4	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	84 14 1 0	70 27 2 1	83 15 1 0	71 26 2 0	61 35 4 1	66 29 5 1	43 44 10 1
5	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	72 25 2 1	53 42 3 2	71 27 2 0	55 41 3 1	43 50 5 2	49 43 6 2	27 57 12 3
6	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	67 27 2 3	47 44 3 5	67 30 2 1	51 44 3 2	38 52 5 4	43 46 6 4	23 57 11 9
7	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	49 36 6 8	29 48 9 12	49 40 8 3	33 52 10 4	22 54 15 9	25 48 18 9	11 48 26 15
8-10	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	35 34 10 18	18 42 15 23	37 40 15 8	23 49 19 9	14 46 24 16	15 40 28 17	6 34 35 24

… lack of sufficient data to calculate probability

Reference: Partin AW, Kattan MW, Subong EN, Walsh PC, et al. Combination of prostate-specific antigen, clinical stage and Gleason score to predict pathological stage of localized prostate cancer: A multi-institutional update. JAMA 1997;277:1445-1451. Copyrighted 1997, American Medical Association. Reprinted with permission.