Predicting Pathologic Stage

Partin Coefficient Table III: PSA = 10.1 – 20.0 ng/ml

This table shows the probability of having each of the four pathologic stages of prostate cancer based on Gleason score, clinical stage and a PSA level between 10.1 and 20.0 ng/ml.

Examples

• A man with a PSA level of 13.3 ng/ml, a Gleason score of 3 and a clinical stage of T1c has a 75% chance of having organ-confined disease.
  
  
• A man with a PSA level of 18.7 ng/ml, a Gleason score of 6 and a clinical stage of T2c has a 9% chance of seminal vesicle involvement.

PSA = 10.1 – 20.0 ng/ml

Probability of Pathologic Stage (%)

		Clinical Stage
Gleason score	Pathologic stage	T1a	T1b	T1c	T2a	T2b	T2c	T3a
2-4	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	76 20 2 0	58 36 4 2	75 22 2 0	60 35 4 1	48 43 7 1	53 37 8 1	… … … …
5	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	61 33 3 3	40 50 5 5	60 35 3 1	43 50 5 2	32 57 8 4	36 51 9 4	18 59 15 7
6	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	… … … …	33 49 4 13	55 38 4 3	38 52 5 4	26 57 7 10	31 50 9 10	14 54 14 18
7	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	33 38 8 18	17 46 11 24	35 45 12 8	22 55 14 9	13 51 18 17	15 45 22 18	6 40 28 26
8-10	Organ-confined disease Established capsular penetration Seminal vesicle involvement Lymph node involvement	… … … …	9 33 15 40	23 40 20 16	14 46 22 17	7 38 25 29	8 33 30 29	3 26 34 37

… lack of sufficient data to calculate probability

Reference: Partin AW, Kattan MW, Subong EN, Walsh PC, et al. Combination of prostate-specific antigen, clinical stage and Gleason score to predict pathological stage of localized prostate cancer: A multi-institutional update. JAMA 1997;277:1445-1451. Copyrighted 1997, American Medical Association. Reprinted with permission.