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Prostate Cancer

Prostatitis

Prostatitis is the general name for an inflammation of the prostate gland. According to the National Institute for Diabetes and Digestive and Kidney Diseases, prostatitis may account for up to 25 percent of all office visits by young and middle-aged men with genitourinary complaints.

Prostatitis may be acute or chronic. Some types of prostatitis are caused by a bacterial infection and others are not. How the prostate becomes infected is not clearly understood. It is possible that infected urine may flow backward from the urethra into the prostatic ducts of the prostate gland. Rectal bacteria may also find its way into the prostate.

Prostatitis is not contagious and is not considered to be a sexually transmitted disease.


Types of prostatitis

  • Acute bacterial prostatitis
    The least common type of prostatitis, but the easiest to diagnose and treat effectively. It is caused by a bacterial infection and characterized by a sudden and severe onset of symptoms, including chills and fever; blood in the urine; lower back pain; pain in the perineum (area between the scrotum and rectum); or extreme pain, urgency, or difficulty with urination. Men with these symptoms need to seek medical attention immediately, as hospitalization may be required. Acute bacterial prostatitis is treated with antibiotics and usually responds quickly to treatment.

  • Chronic bacterial prostatitis
    Also caused by bacteria and is one of the most common causes of recurring urinary tract infections in men. Symptoms may include urinary difficulty, frequency or urgency; pain or burning with urination; and pain in the lower back, perineum, penis, scrotum and/or pubic region. These symptoms are usually not evident until sufficient amounts of bacteria have built up. Chronic bacterial prostatitis is treated with antibiotics, but it often recurs.

  • Chronic nonbacterial prostatitis
    The most common type of prostatitis, but the least understood. It is not caused by bacteria; therefore, it cannot be treated with antibiotics. The cause of chronic nonbacterial prostatitis is unknown. Its symptoms are similar to those of chronic bacterial prostatitis: urinary difficulty, frequency or urgency; pain or burning with urination; and pain in the lower back, perineum, penis, scrotum and/or pubic region. Chronic nonbacterial prostatitis may be inflammatory or noninflammatory and symptoms may go away and return without warning.

  • Prostatodynia
    Also known as prostate pain, prostatodynia produces symptoms similar to nonbacterial prostatitis but tests show no sign of inflammation, as they do in all types of prostatitis. Prostatodynia may be caused by muscle spasms in the bladder neck or pelvis.


Risk factors for prostatitis

Certain conditions or medical procedures increase the risk of contracting prostatitis. You are at higher risk for getting prostatitis if you:

  • recently have had a medical instrument, such as a urinary catheter (a soft, lubricated tube used to drain urine from the bladder), inserted during a medical procedure
  • engage in rectal intercourse
  • have an abnormal urinary tract
  • have had a recent bladder infection
  • have an enlarged prostate (BPH).


Testing for prostatitis


Testing for prostatitis involves looking for signs of inflammation or infection in the fluid secreted by the prostate gland and in the urine. The following tests are used.

  • Microscopic analysis of expressed prostatic secretions (EPS)
    The fluid produced by the prostate gland is examined for infection. This fluid is obtained by prostate massage, which is also done during a digital rectal examination. The doctor vigorously massages or presses on the prostate gland to express, or force, fluid out of the prostate, into the urethra and out of the body through the penis. These expressed prostatic secretions (EPS) are collected on a glass slide and examined under a microscope for signs of infection, such as abnormally high levels of infection-fighting white blood cells.

    Prostate massage is not performed in the case of acute bacterial prostatitis, which is not only painful but could cause the release of bacteria into the bloodstream. Because a urinary tract infection often accompanies acute bacterial prostatitis, the bacteria would show up in a simple urine test.

  • Urinalysis/urine culture
    Prostatitis is most commonly diagnosed through a three-part urine test which collects urine from the urethra and the bladder, as well as urine containing fluids from the prostate. The procedure is as follows:
  1. The patient's first ounce of urine comes from the urethra and is collected in one container.
  2. The midstream sample of urine comes from the bladder and is collected in another container.
  3. The patient urinates in a toilet until his bladder is almost, but not completely, empty.
  4. Before the patient completely empties his bladder, he is given prostate massage (see above), during which expressed prostatic secretions are collected on a glass slide.
  5. The patient completely empties his bladder in the third container, which contains prostatic fluid as well as urine.


Test results for prostatitis

Comparing the urine samples to the expressed prostatic secretions helps determine whether the infection, if any, is coming from the urethra, bladder, or prostate gland.

  • In chronic bacterial prostatitis, white blood cells will be found in the urine or prostatic fluid.
  • In nonbacterial prostatitis, the prostatic fluid will have high levels of white blood cells and show other signs of inflammation, but no bacteria.
  • In prostatodynia, urine and prostatic fluid will look normal.

The Prostate Cancer pages of this Web site are part of the Comprehensive Prostate Cancer Awareness Program (CPCAP), a major regional effort to reduce the rates of death and illness caused by prostate cancer in southwestern Pennsylvania. Funding for CPCAP is provided by a grant from the Commonwealth of Pennsylvania.


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