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Prostate Cancer

Determining Your Choice of Treatment

Men diagnosed with prostate cancer are confronted with a number of daunting treatment choices. Different treatments may yield comparable results, but bring a host of different, potentially unpleasant side effects. Some new treatments look promising but haven’t been around long enough to demonstrate long-term effectiveness.

The research and medical communities offer no definitive answer on the one "best" treatment, particularly in early-stage cancer confined to the prostate. Medical centers with extensive experience in a specialized treatment may report significantly better outcomes than centers with less experience.


Making an informed treatment decision

The more you know, the better you will be able to make an informed decision about the prostate cancer treatment most appropriate for you.

  • Learn everything there is to know about your own cancer, including your clinical stage, PSA level and Gleason score.

  • Explore all your treatment options. Realize that many treatment options have not been compared to each other in unbiased, randomized studies. Therefore, there is going to be some degree of bias in many of the research studies you encounter. This web site attempts to provide research studies with the most optimistic view of each treatment option, based on the professional literature.

  • Your local library or bookstore can be a useful resource for general information on prostate cancer and cancer survivorship. Many hospitals have patient libraries with books, brochures and videos explaining prostate cancer and treatment options.

  • Talk to your doctor. Come prepared with a list of questions; bring a notebook or a tape recorder so you have a permanent record of the answers to review at your leisure.

  • Get a second opinion and a third if you need it. Be suspicious if your doctor recommends that you not seek other opinions.
  • Take the time to include your wife or significant other in your search for information and in your decisions.

  • Research the specialists who may be treating your prostate cancer. Does the specialist have a proven track record in that procedure? Find out about the specialist’s training, how often he or she has performed the procedure and how well the patients have fared after treatment.

  • Prostate cancer support groups give you the chance to talk to other men who have faced the same questions about prostate cancer.


Factors in decision making

The most effective and appropriate prostate cancer treatment for you depends on a number of factors:

  • Stage
    After the biopsy, the next step is to determine the cancer’s stage: the size of the tumor and how far it has spread. The stage of your prostate cancer is one of the most important factors in deciding how best to treat it.

    When prostate cancer is confined within the prostate gland and hasn't spread to other parts of the body, radical prostatectomy and radiation therapy may be effective treatments. However, when prostate cancer has spread outside the prostate gland, early-stage options may not stop the cancer from spreading further. Advanced cancers respond more effectively to other localized treatments, such as radiation, or to systemic treatments such as hormone therapy and chemotherapy.

  • Age
    A 55-year-old man and an 85-year-old man, both diagnosed with localized prostate cancer that may spread in 10 years, may come to completely different and equally valid decisions about how to treat it. Aggressive treatments for prostate cancer can produce unpleasant side effects and potential complications and may destroy a level of health more easily recovered in a younger man. An 85-year-old man may be less concerned about a cancer that may spread by the time he is 95. These considerations may lead a 55-year-old to opt for surgery or radiation, while an 85-year-old may opt for watchful waiting.

  • Overall health
    Men in good health have a better chance to recover more quickly and completely from prostate cancer treatment than men in poor health. Aggressive treatment may not greatly benefit men with other serious medical conditions or whose life expectancy is less than ten years. In fact, such treatment may produce unpleasant -- and unnecessary -- complications that could seriously compromise the quality of the remaining years of life.

  • Priorities
    Deciding prostate cancer treatment is ultimately a personal decision only you can make, based on what's most important to you. In addition to considerations about age and general health, you must consider quality of life issues, not the least of which is deciding between living with the cancer and facing the potential side effects of treatment.


The Prostate Cancer pages of this Web site are part of the Comprehensive Prostate Cancer Awareness Program (CPCAP), a major regional effort to reduce the rates of death and illness caused by prostate cancer in southwestern Pennsylvania. Funding for CPCAP is provided by a grant from the Commonwealth of Pennsylvania.


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