Twenty-three Cancer Researchers Receive Funding from the Hillman Fellows Program for Innovative Cancer Research

PITTSBURGH , March 23 – The second wave of Hillman Fellows at the University of Pittsburgh Cancer Institute (UPCI), a group of 23 researchers, has received grants totaling $2 million to pursue novel, high priority cancer projects. The grants are part of a $20 million gift donated to UPCI by the Henry L. Hillman Foundation and the Hillman Foundation that established the Hillman Fellows Program for Innovative Cancer Research in 2005.

The Hillman Fellows Program was created to fund cancer research that, although in its early stages, promises to have a far-reaching impact on the field. The program has funded research in cancer stem cell biology, biomarkers for the early detection of cancer, cancer vaccines and cellular therapies, methods for diagnosing and monitoring cancer, and programs in cancer prevention that are based on genetic and environmental risks for disease.

The 2006 Hillman Fellows and their research topics include:

Lisa Butterfield, PhD and John Kirkwood, MD - Determinant spreading in melanoma immunotherapy
William Chambers, PhD - Evaluating the effects of stress on spontaneous breast cancer development
Shi-Yuan Cheng, PhD - Signaling mechanisms in glioma invasion
Albert Deleo, PhD - Aldehyde dehydrogenase type 1, a novel tumor antigen for development of vaccines for immunotherapy of squamous cell carcinoma of the head and neck
Stefan Duensing, MD - Genomic instability induced by tumor viruses: Identification of molecular mechanisms and possible therapeutic implications
Seymour Garte, PhD and Emanuela Taioli, MD, PhD - Interactions between genetic factors and environmental exposures in human cancer causation
Elieser Gorelik, MD, PhD - A new approach in anticancer drug screening
Pamela Hershberger, PhD - Improving vitamin D as a treatment for lung cancer by preventing its destruction within tumor cells
Bo Hu, PhD - Target deregulated transcription factors and co-factors for cancer prevention
Michael Lotze, MD - Improving on interleukin-2 therapy for cancer
Ruth Modzelewski, PhD - Tumor blood vessel targeting as a strategy for cancer intervention to improve diagnosis and targeted treatment options
Mark Nichols, PhD - Understanding resistance to antihormone therapy in breast cancer treatment: Developing new RNA interference tools and drug screens to find novel and effective therapies
Donna Posluszny, PhD - Brief psychosocial intervention for head and neck cancer patients and partners
Hannah Rabinowich, PhD - Harnessing Ncl-1 anti-apoptotic mechanisms for the protection of T lymphocytes from prostate cancer-induced dysfunction
Sanjay Srivastava, PhD and Shivendra Singh, PhD - Prostate cancer prevention by guggulsterone, a constituent of Indian ayurvedic medicinal plants
Richard Steinman, MD, PhD - The role of post-transcriptional regulation in differentiation and cancer
Nikola Vujanovic, MD, PhD - Cancer immunotherapy by stimulation NK cell-dendritic cell cross talk
Yong Wan, PhD - Functional proteomic study of proteolysis in DNA damage/repair and tumor formation
Qingde Wang, MD, PhD - Regulation of NF-xB signaling pathway in cancer stem cells and its clinical implications
Joel Weissfeld, MD - Follow-up research-based lung cancer screening at the University of Pittsburgh Cancer Institute

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