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Lymphoma

Lymphoma is a cancer that develops in the lymph system, which is part of the body’s immune system, and often presents in the form of a solid tumor of cells.

What is lymphoma?

It is estimated that 74,490 men and women were diagnosed with lymphoma in 2009. Lymphoma is a group of cancers that affects the cells that play a role in a person’s lymphatic system, the network of the body that works to fight infection. Lymphoma is a malignant transformation in the lymphocytes, a type of white blood cell, which when healthy, recognizes and destroys infections. As these abnormal cells multiply, they form a tumor. Often in lymphoma, abnormal lymphocytes travel via the lymphatic system to other organs such as the spleen. Lymphoma can be classified into two types: Hodgkin lymphoma and non-Hodgkin lymphoma.

Types of lymphoma

The two types of lymphoma have similar symptoms and characteristics. However, they can be distinguished under a microscope by which type of white blood cell is abnormally affected. The two types of lymphoma are:

  • Hodgkin lymphoma — A rarer form of lymphoma which is distinguished by the presence of abnormal white blood cells called Reed-Sternberg cells. It tends to affect younger people. Hodgkin lymphoma tends to spread to lymph nodes in a predictable way.
  • non-Hodgkin lymphoma — More common and also involves the presence of abnormal white blood cells. It tends to affect older people, and the cancer cells can spread unpredictably through the lymph nodes. Non-Hodgkin can further be classified into three groups:
    • Indolent (low-grade) lymphomas grow slowly, and generally do not cause symptoms. However, indolent lymphomas can become aggressive over time.
    • Aggressive (also called intermediate-grade) lymphomas grow quickly, and cause severe symptoms.
    • Highly-aggressive (high-grade) lymphomas grow very quickly, and generally require immediate care.


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